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A diabetes drug may also be a promising discussion forobesity — in a new study , people taking the drug lost a stunning 15 % of their body weighting , which is more than has been see with any other obesity drug on the market .
The drug , known as semaglutide , is an injectable medication that ’s already approved to help control line of descent sugar levels in mass withType 2 diabetes . But the drug also suppresses appetite .
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In the newfangled study , bring out Wednesday ( Feb. 10 ) inThe New England Journal of Medicine , researchers randomly assigned 1,961 grownup who were rotund or fleshy to receive semaglutide or a placebo as an injectant once a hebdomad for 68 hebdomad . Participants also received counseling sessions once a month to help them adhere to a reduce - calorie dieting , and they were encouraged to increase their physical activity .
By the end of the study , those who received semaglutide lost 14.9 % of their trunk weight , on mediocre , equate with just 2.4 % of torso weight in the placebo chemical group .
Five other drugs are approved to treat obesity , but even the most effective of these drugs lead in about 7.5 % weightiness loss , according toThe New York Times . And these drug can typically be used for only scant periods of clock time , the Times reported . For exemplar , the free weight loss drug phentermine is typically taken for 3 to 6 weeks , according to theNational Institutes of Health , a much little amount of time than the 68 - calendar week treatment with semaglutide used in the study .
" This is the beginning of a new epoch of effective handling for obesity , " Dr. Robert F. Kushner , an obesity research worker at Northwestern University Feinberg School of Medicine , who led the field of study , told the Times .
People who bring semaglutide were more likely to experience GI side effects , including nausea , diarrhea , puking and stultification , compared with the placebo group . But these side effects run to be temporary .
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The study also did not look at the drug ’s effects beyond 68 weeks , and people would in all probability require to stay on the drug for biography to prevent their exercising weight from coming back , the Times reported .
And weight loss drug that appear to do well in trials may not be as effective in existent - world mise en scene , according to CNN . What ’s more , several weight red drugs that achieved favorable reception from the Food and Drug Administration were afterwards recalled because of side force , CNN reported .
The study was funded by the God Almighty of semaglutide , Novo Nordisk . The Danish pharmaceutical company has already put in an program with the FDA for approving of semaglutide for chronic weight unit management , allot to CNN .
Originally publish on Live Science .
